Image Measurements on ceiling mounted cooling systems
Image Free Cooling by Circuit of Refrigerant
Image Low Temperature Tribology
Image Solar-electric Cooling
Image Laughing gas as an alternativ refrigerant for R-23
Image Helium extraction from natural gas
Image Solar Cooling
Image State of system and failure analyses
Image Thermostatic Expansion Valves
Image Prüflabor Wärmepumpen at ILK Dresden
Image Optimization of pharmaceutical freezing processes
Image Hydrogen test area at ILK Dresden
Image Membrane-based Air Conditioning
Image Components for Cold Storage Systems
Image Natural gas vehicle for long distances
Image Thermal engines

You are here:   /  Home


Optimization of pharmaceutical freezing processes

for Industry and Research Institutes

Johannes Heidingsfelder

+49-351-4081-618

On intermediate bulk and final bulk state

The goal is the product-specific characterization of final / intermediate bulk freezing processes within biotechnological production and its optimization with respect to the residual product activity.

For this purpose we have developed an innovative method for the numerical simulation of the freezing process and the activity loss of the protein as well as the analysis of protein aggregation. The bilateral approach allows the prediction of the product loss depending on the harmful mechanism of the freezing process.

This unique approach realizes:

  • Resource-saving optimization of cryopreservation processes and storage of biopharmaceutical product solution
  • High-resolution process analytics and numerical simulation of pharmaceutical freezing processes
  • Development and optimization of lyophilization processes

Extensive methodical competence in laboratory- and process analytics allow:

  • Material pick-up analysis
  • Detection of protein aggregation
  • ... and much more

Your Request

Further Projects

Image

Industrie-4.0-Membran-Wärme-und-Stoffübertrager (i-MWÜ4.0)

Vernetzung des gesamten Lebenszyklus einer multifunktionalen RLT-Komponente

Image

Thermostatic Expansion Valves

Does the TXV function correctly?

Image

Performance tests of refrigerant compressors

Does your compressor perform well?

Image

State of system and failure analyses

Cause of the failure unknown?


Contact

Institut für Luft- und Kältetechnik - Gemeinnützige Gesellschaft mbH
Bertolt-Brecht-Allee 20, 01309 Dresden


Secretary to the Management

+49-351-4081-520

+49-351-4081-525

Bild Zuse Mitglied Bild SIG